Examining obesity-related risk factors using the 4Ms framework (metabolic, mechanical, mental, milieu) in children with excess weight
Project Lead: Katherine Morrison
Timeline: January 2016 – December 2016
Objectives: To identify the presence of adverse health outcomes, namely metabolic, mechanical, mental health, and social milieu and compare and contrast 4Ms in children across the range of excess weight.
Research Plan: From cross-sectional baseline data collected from children and families enrolled in CANPWR, health measures that meet the 4Ms framework: metabolic (fasting levels of glucose, insulin, total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides, systolic and diastolic blood pressure, liver enzymes,); mechanical (sleep quality and apnea, musculoskeletal problems, gastroesophageal reflux disorder, physical functioning); mental health (depression, anxiety, attention deficit hyperactivity disorder, learning disability, emotional functioning); and social milieu (household income, parent education and health status, school and social functioning, inter-personal interactions [e.g., bullying]) will be collected.
Outcomes: This study will examine a diverse set of risk factors associated with obesity across a spec- trum of excess weight for children enrolled in CANPWR, contribute data to determine criteria for severe obesity based on health risks, and quantify the burden of illness associated with severe obesity in children to inform development of clinical tools and decision-making.